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Caution is advised when PDE5 inhibitors are co-administered with alpha-blockers. PDE5 inhibitors, including Viagra 25 mg, and alpha-adrenergic blocking agents are both vasodilators with blood pressure lowering effects. When vasodilators are used in combination, an additive effect on blood pressure may occur. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you.

Physicians should advise patients of the potential for VIAGRA to augment the blood pressure lowering effect of alpha-blockers and anti-hypertensive medications. Concomitant administration of VIAGRA and an alpha-blocker may lead to symptomatic hypotension in some patients. The AUC of the active metabolite, N-desmethyl sildenafil, was increased 62% by loop and potassium-sparing diuretics and 102% by nonspecific beta-blockers. These effects on the metabolite are not expected to be of clinical consequence.

Viagra is best taken on an empty stomach one hour before sex. Eating food directly before taking Viagra will delay its absorption. This can delay the onset of action and reduce the effectiveness of the drug. Swallow the tablet whole with a glass of water, and if you have consumed a heavy meal, wait a couple of hours. You may be disappointed that Viagra hasn’t worked the first time but try to remain patient. Give yourself time to become more comfortable and mentally adjust to the idea of taking a pill before sex.

Only consider this option under the guidance of a doctor or pharmacist. Offers the same effectiveness in treating erectile dysfunction (ED) without paying a premium for the brand name. The choice between Sildenafil 100mg and 50mg depends on several factors, including the severity of your condition, medical advice, and your personal preferences. This is especially true when a woman is on the verge of menopause.

A stronger CYP3A4 inhibitor such as ketoconazole or itraconazole could be expected to have greater effect than that seen with saquinavir. The results from this pilot study are shown in Table 3