The presence of luck-based mechanics in a strategy game can be both a blessing and a massive frustration.

Understanding exactly where randomness factors into the equation allows top players to mitigate its negative effects.
Initial Deck Shuffling
If your opponent rushes the bridge and all your cheap defensive counters are at the bottom of your deck, you lose the tower.

Once the initial hand is played, the rotation becomes fixed, and pure skill and memory take over.
Learn to adapt to bad RNG.Track the opponent's rotation after the first cycle.Some RNG is healthy for the game. Unit Targeting and Pathfinding
Another subtle layer of RNG comes from the slight inconsistencies in how the game's AI handles pathfinding.

Leaving a slight margin for error in your defensive placements is the best way to handle AI unpredictability.
Genre TypeLevel of LuckAuto-BattlersSkill comes from long-term statistical managementStandard Tower RushVery Low - Only the starting hand is randomized Embracing the Chaos
The most important skill regarding RNG is learning how to control your emotions when luck inevitably turns against you.

Focus on improving your timing and placement, and let the RNG sort itself out in the long run.